Chair and Case Operator Devi Nair (Jonesboro, US) led this session on the Globe Cardium System, a novel single-shot pulsed field ablation (PFA) solution integrating pacing, mapping, and ablation. She was joined by panellists Jason Andrade (Vancouver, CA), Luigi Di Biase (New York, US), and Mohit Turagam (New York, US). The session focused on the capabilities of this 30 mm, 122-electrode array, which allows for customisable energy delivery based on real-time contact mapping. Dr Nair highlighted its ability to isolate pulmonary veins (PVs) in a single application while also treating areas beyond PVs, such as the posterior wall and mitral isthmus. The catheter, which navigates via a 16 French sheath, provides high-density voltage and wavefront mapping, ensuring lesion depth and precision while minimising complications such as haemolysis.

The case presented involved a 54-year-old male with paroxysmal atrial fibrillation enrolled in the IDE trial. The faculty discussed the system’s advantages, including its ability to deliver therapy selectively while avoiding unnecessary energy application to non-contact areas. The panel debated procedural efficiency, the role of high-density mapping, and the benefits of the catheter’s bidirectional deflection for optimising contact. They also explored its potential beyond pulmonary vein isolation, including mitral and cavotricuspid isthmus lines. The discussion concluded with insights into selecting PFA systems based on efficiency, safety, and workflow integration, emphasising the importance of streamlined procedures with precise lesion delivery.